LOX and breast cancer: Gene expression data from 1,160 human breast cancer specimens in the TCGA database were used to compare levels of TAZ mRNA with the expression of CXCR3, L1CAM, LOX, P4HA1, P4HA2, PDGFB, PLOD1, PLOD2, SLC2A1, and VEGFA mRNA, which are all HIF-regulated in breast cancer cells (Fig. S1A).