Following the subcutaneous implantation of 1×103 and 1×104 BT-549 cells, SATB1 depletion in the cells significantly reduced the success of engraftments (Fig. 4C), while subsequent to the subcutaneous implantation of 1×106 BT-549 cells, SATB1 knockdown significantly reduced tumor size after 21 days (Fig. 4D). This evidence concerns the gene SATB1 and neoplasm.