A notable observation was that following the subcutaneous implantation of 1×104 and 1×105 MCF-7 cells, SATB1 overexpression in the cells significantly increased the success of engraftments (Fig. 4A), and subsequent to the implantation of 1×106 MCF-7 cells, SATB1 overexpression significantly increased tumor size after 21 days (Fig. 4B). The gene discussed is SATB1; the disease is neoplasm.