Considering this short list as a BRCA1-IRIS-overexpression signature in TNBC tumors, we conducted an association assessment of this signature and disease-free survival (DFS) using a combined breast cancer cohort from seven Gene Expression Omnibus (GEO) studies (GSE2034, GSE2603, GSE3494, GSE4922, GSE6532, GSE7390 and GSE12093). This evidence concerns the gene BRCA1 and breast cancer.