Notwithstanding, the relationship between insulin resistance markers and adiponectin, previously shown[5], was demonstrated here, with the HMW:TA ratio shown to be significantly lower in patients (in all groups) with established insulin resistance (HOMA-IR greater than 1.95[21]) and also significantly lower in patients with BMI greater than or equal to 25 than in those with lower BMIs. This evidence concerns the gene ADIPOQ and Insulin resistance.