The median time to recurrence (TTR) was 34.8 (95% CI: 27.5–42.0) months for patients with HCC who were positive for PKM2 and 52.9 (95% CI: 48.4–57.5) months for patients with HCC who were negative for PKM2 (P < 0.0001, log-rank test, Figure 2B). Here, PKM is linked to hepatocellular carcinoma.