Of the 21 patients assessed for APLP2 expression in primary pancreatic tumors with matched liver metastases, 8 of 21 patients (38.1%) had positive APLP2 expression in both the primary tumor and the liver metastasis, whereas a lesser percentage (5 of 21, or 23.8%) had negative expression in both. The gene discussed is APLP2; the disease is pancreatic neoplasm.