We thus also analyzed the genes in the pathways co-expressed with c-MYC in the 5 data sets [29, 32, 33, 59, 60] and our data suggest that c-MYC and PDGFRβ activate distinct signaling pathways in MBs (Table 1, Supplemental Tables S3, S4). This evidence concerns the gene PDGFRB and Mobius syndrome.