Although most reports indicate that LDH-B expression is decreased in breast tumors [17], integrative genomic analysis found that LDH-B expression is higher in the basal-like versus luminal subtype of cells in triple-negative breast cancers (TNBCs), and silencing of LDH-B expression in MDA-MB-231 cells decreases tumor growth [19]. This evidence concerns the gene LDHB and breast neoplasm.