Migration inducting gene-7 (MIG-7) protein, a potential mediator of metastasis [5-7] is functionally associated with COX-2/prostaglandin E2 (PGE2)-induced lung cancer metastasis through phosphorylation of Akt and glycogen synthase kinase-3 β (GSK-3β), activation of wnt/β-catenin/TCF-4/LEF-1 signaling and decrease in the activity of protein phosphatase 2A (PP2A) [8]. This evidence concerns the gene BCAR3 and lung cancer.