At the same time, the real-time PCR analyses for all 41 patients did not show any significant alterations of CA9, CDH2, ETS2, LDHA, PGF, PPP1R15A, SERPINB2, VEGFC, OCLN FOXC2 and BCL211 genes in tumor tissues when compared with healthy tissue samples (Table 1)(Figure 2). The gene discussed is CDH2; the disease is neoplasm.