To determine if increased GRIM-19 expression alters the metabolic and proliferative activity of HNSCC cells, we generated stable JHU-028 cells that overexpressed either HA-tagged GFP cDNA (HA-GFP) or HA-tagged GRIM-19 cDNA (HA-GRIM-19). Here, NDUFA13 is linked to head and neck squamous cell carcinoma.