PTPRC and infection: In the epidermis there were also significantly higher numbers and percentages of CD45+ leukocytes within 24 h of infection than in naïve tissue where resident leukocytes (i.e. γδ T cells and LCs) were a relatively minor population (Fig. 1Ca, Cb; number of CD45+ cells: ANOVA F: 39.22, P < 0.001 and percentages: ANOVA F: 6.491, P = 0.002).