SRC and infection: The Akt1KO/Src (Y527F) cells and Akt1/2KO Src (Y527F) cells have the ability to form podosomes and rosettes soon after infection with Src (Y527F) , although at a much reduced level (Figure 2F); however, the number of cells producing podosomes and rosettes disappear the longer they are in culture (Figure 2G).