Neuropilin-1 expression is reported to be specific for pDCs in humans13 and has been found to be highly expressed in diverse solid tumors, as prostate, breast, pancreatic, lung, ovarian and gastrointestinal carcinomas.14,15 Increased expression of Neuropilin-1 has been correlated with tumor growth and invasiveness.16 The gene discussed is NRP1; the disease is digestive system carcinoma.