GSTM1 and thalassemia: By analyzing, we found that Hb levels of β-thalassemia patients were significantly lower than α-thalassemia patients, indicating that β-thalassemia patient's condition is generally more serious than α-thalassemia patients, which may be partly explained by the fact that the clinical efficacy of α-thalassemia was better than that of α-thalassemia patients by using Yisui Shengxue Granule, but it needs a large sample of clinical trials by further verification.