In an effort to validate and expand these results, Locasale et al. [8] assessed PHGDH protein expression in 106 breast cancer tumor samples using immunohistochemistry correlated with mRNA expression to find that high PHGDH expression associated significantly with triple-negative (P = 0.002) and basal subtypes (P = 0.004) but did not associate with general parameters such as metastasis (as was previously reported) or with tumor size. Here, PHGDH is linked to neoplasm.