Deleted in lung and esophageal cancer 1 (DLEC1) is a tumor-suppressor gene which suppresses tumor growth or reduces the invasiveness of cancer cells and promoter hypermethylation has been shown to be responsible for the silencing of DLEC1 in ovarian cancer and nasopharyngeal carcinoma [14]. The gene discussed is DLEC1; the disease is nasopharyngeal carcinoma.