For example, in our analysis of the TCGA Ovarian Cancer data set, amplification of the c-MYC oncogene was frequently associated (in 58% of mutated tumors) with an increase in the expression of the phenotype gene BCAT1, an amino acid transaminase that produces branched-chain L-amino acids required for cell proliferation. The gene discussed is BCAT1; the disease is ovarian carcinoma.