S100B and brain injury: The detection of S100B in the saliva has opened new possibilities for the assessment of this protein in perinatal medicine, and the purpose of the International “Cooperative Multitask against Brain Injury of Neonates” (CoMBINe) Study was therefore to investigate whether the measurement of S100B levels in salivary fluid collected from asphyxiated full-term newborns may constitute a useful tool for the early detection of neurological abnormalities.