While not associated with markers of endothelial activation, PvLDH was correlated with the systemic inflammatory markers IL-6 (ρ = 0.27, P = 0.045) and IL-10 (ρ = 0.28, P = 0.035), and, in contrast to peripheral parasitemia, was inversely correlated with baseline platelet count (ρ = −0.26, P = 0.045) and with platelet nadir (ρ = −0.27, P = 0.035). Here, IL6 is linked to parasitic infectious disease.