BECN1 and infection: However, in adjacent sections these regions were absent for p62 and LC3 when WT virus was used (Fig. 5C, top row), but detectable in adult brains after infection with mutant HSV-1 deleted for beclin 1 binding (dBBD) (Fig. 5C, middle row), consistent with the expected inhibition of autophagy by WT but not dBBD virus.