We hypothesized that the type 1 proinflammatory environment and the increased TLR-4 signaling mediated by human resistin might therefore impair intestinal immunity to Nb. To this end, we monitored the time course of Nb colonization in the small intestine of hRetnTg+ and hRetnTg− mice by assessing the parasite egg burdens in the feces followed by sacrifice of the mice at day 9 post-infection. This evidence concerns the gene TLR4 and infection.