RGS16 and familial pancreatic carcinoma: We chose to study the function of RGS16 in pancreatic cancer because only 5.7% (1 out of 17) of pancreatic tumors with lymph-node metastases had expression of RGS16 compared to 70.6% (12 out of 17) of pancreatic tumors with non-metastasized pancreatic cancer [26].