LMNA and Hutchinson-Gilford progeria syndrome: Because it is likely that cells from aged individuals express progerin at lower levels than cells from HGPS patients [18], we consider our transduced GFP-Progerin MIAMI cells provide a suitable model to assess the effects of progerin expression in the context of physiological aging in a defined stem/progenitor cell population, with implications to age-related disorders during organismal aging.