After multivariable analyses, only the basophil activation markers were retained for severity and threshold, meaning that the BAT alone was more discriminative in predicting the severity (CD63 peanut/anti-IgE, P = .001) and threshold (CD-sens, P = .020) of allergic reactions to peanut than the other allergy tests or the combination of the BAT with the other allergy tests (Table III). This evidence concerns the gene IGHE and allergic disease.