Preincubation of human pharyngeal carcinoma Detroit 562 cells with 200 μ M Curcumin for 5–60 min resulted in complete suppression of the release of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, IL-8, monocyte chemoattractant protein 1 (MCP-1), granulocyte macrophage-colony stimulating factor, and VEGF. Here, CCL2 is linked to carcinoma of pharynx.