In preeclampsia, the prevalence of IL-17-producing CD4, CD8, and NK cells is elevated in peripheral blood compared with normotensive pregnant women (152), and the Th1/Th2 and Th17/Treg balance is shifted toward increased immunity determined by a Th1 response, elevated Th17 T cells and reduced Treg numbers, possibly affecting the uterine microenvironment conjointly with dNK cells (152). The gene discussed is CD4; the disease is preeclampsia.