Vγ2Vδ2 cells have been expanded with 2M3B1PP and infected with γ-retrovirus to transduce TCRαβ chains with specificity toward MAGE-A4 peptide, but co-transduction with CD8 was required in order to transfer significant MHC Class-I-restricted recognition of MAGE-A4 peptide-pulsed tumor cells (90, 91). The gene discussed is MAGEA4; the disease is neoplasm.