However, a link between membrane trafficking and other genes implicated in the CNMs is not immediately obvious, and the communality of clinico-pathological features between MTM1, DNM2, and BIN1-related CNM on one hand and the more recently reported forms due to recessive mutations in RYR1 and TTN on the other hand remains currently unaccounted for on the molecular level. Here, DNM2 is linked to centronuclear myopathy.