Previous study illustrated the protective effect of aqueous extract of lavender on eliminating Aβ in in trahippocampal Aβ-injected rat model of AD (20, 30), here we evaluated the mechanism of this beneficial effect related to expression some protective proteins such as Snca, Hspa, Prdx2, Apoa1, Atp5a1 and NF-L as protein target for monoterpen agents (rosmarinic acid, caffeic acid, luteolin 7-Oglucoside,methyl carnosoate (69)) in LA that trigger mechanisms such as anti-lipid peroxidation, antiglutamatergic and anti-inflammatory activities (69). The gene discussed is ATP5F1A; the disease is Alzheimer disease.