NF-L (Figure 2d) binds to Mapk12 (mitogen-activated protein kinase 12), Mapk13, Mapk14, Nefh (neurofilament), Nefm, Prph (peripherin) and Prph2 which are involved in pathway associated to Amyotrophic Lateral Sclerosis (ALS). The gene discussed is MAP3K12; the disease is amyotrophic lateral sclerosis.