Concurrent treatment with cisplatin and intratumoral injection (i.t.)of E7 peptide in C57BL/6 mice bearing E6/E7-expressing TC-1 tumors generated significantly more E7-specific IFN-γ-secreting CD8+ T cells and could cure many mice, whereas those treated with either therapy alone did not generate similar tumor growth control. The gene discussed is CD8A; the disease is neoplasm.