NFKB1 c.-798_-795delATTG ins/del and del/del genotypes, and IL-10 c.-854 TT genotype were associated with increased breast cancer risk, while IL8 c.-352 TT genotype, TNF c.-418 GA and AA genotypes, and c.-488 GA genotype were significantly associated with a reduced risk (Table 3). This evidence concerns the gene TNF and breast cancer.