ACE and obesity due to melanocortin 4 receptor deficiency: Score was developed as a sum of points assigned to each preoperative variable identified by multivariate model including preoperative need for intraaortic balloon pump (IABP), increased pulmonary vascular resistance (PVR), inotrope dependency, obesity, DT, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACE/ARB), and beta-blocker (27).