Nonetheless, our observation that Nox5 is abundantly expressed in LNCaP and PC‐3 PCa cell lines is supported by immunohistochemical data using an extensively validated antibody and supported by data from the Human Protein Atlas, which together demonstrate that Nox5 is expressed in the benign and malignant prostatic epithelium in vivo and at abundant levels in clinical PCa. Here, NOX5 is linked to posterior cortical atrophy.