Moreover, the Ca2+ channel TRPV6, which is overexpressed in PCa and correlates with tumor progression and poor prognosis, is also expressed at higher levels in the Nox5‐positive PCa cell lines PC‐3 and LNCaP compared to normal and benign epithelial cells 48, 49, 50, 51. This evidence concerns the gene NOX5 and posterior cortical atrophy.