PPARA and hepatitis C virus infection: Significantly affected pathways in KIRC include taurine and hypotaurine metabolism (Figure 4), neuroactive ligand-receptor interaction, glycosaminoglycan biosynthesis - heparin sulphate, Peroxisome Proliferator-Activated Receptor (PPAR) signalling pathway (Figure 5), and hepatitis C, gastric acid secretion pathway (Table 2).