Targeted analysis of candidate PFD genes was undertaken after next‐generation sequencing of exomic DNA from 18 unrelated index cases with PFDs who were recruited into the UK Genotyping and Phenotyping of Platelets (GAPP) study and diagnosed with platelet abnormalities affecting either Gi signaling (n = 12) or secretion (n = 6). This evidence concerns the gene GNAI1 and polyostotic fibrous dysplasia.