TGFBR2 and colorectal carcinoma: Functionally, we found TGFBR2 acted as a metastasis suppressor and also the effector of miR-301a in CRC cells: knockdown of TGFBR2 induced a significant increase in motility and invasiveness of SW480 cells whereas downregulation of TGFBR2 also elevated the previously abrogated migration and invasion ability initiated by LV-anti-miR-301a in SW620 cells.