GAL3ST1 and metachromatic leukodystrophy: Overexpression of the mouse Gal3st1 cDNA (galactosylceramide sulfotransferase) in oligodendrocytes and Schwann cells of arylsulfatase A (ASA) deficient mice increased sulfatide storage in the nervous system and development of a myelin pathology in the CNS, particularly in the peripheral nervous system (PNS) similar to metachromatic leukodystrophy patients [41].