FOS and fibromyalgia: Up to the present date, this is the first study evaluating preclinical anti-hyperalgesic effect of LEO and LEO/β-CD in experimental fibromyalgia in animal model, besides the goal to elucidate the central nervous system areas involved in this activity by immunohistochemistry for c-fos protein, a useful marker for the control of neuronal activity of the central pathways, particularly in the pain pathway