To determine whether a signature(s) of lymph node metastasis was detectable within individual subtypes, data was evaluated for luminal A (n = 177), luminal B (n = 25), HER2-enriched (n = 47) and basal-like (n = 94) lymph node negative and lymph node positive tumors; normal-like tumors (n = 2) were not evaluated. This evidence concerns the gene ERBB2 and benign neoplasm.