CD44 and urinary bladder cancer: Besides that, we evaluated the expression of CD44 in bladder cancer cell lines and found the expression of CD44 was up-regulated in these cell lines (Figure 1D, p < 0.01), suggesting a negative correlation between the expression of CD44 and miR-34a in bladder cancer cell lines, which was shown in Figure 1E (R2 = 0.5988 p = 0.0412).