The area of cancer cells that were covered by the endothelial cells in the presence of sunitinib was markedly larger than that in normal or VEGF-depleted RFP-HeLa cells in most events of extravasation, and the blood vessel walls concurrently, but slowly, moved toward the embolus-forming RFP-HeLa cells (Fig. 4B; Movie S7). The gene discussed is VEGFA; the disease is cancer.