CRP and nicotine dependence: The SNP we identified in this gene, rs1484464, has been investigated in relation to a number of phenotypes, including tobacco use disorder, smoking cessation, coronary artery disease, lipid metabolism (HDL, total cholesterol, triglycerides) disorders, waist-hip ratio, CRP, glucose levels, insulin resistance, body mass index, blood pressure, and interleukin levels; however, significant associations have not been reported [53]–[62].