Finally, adipokines (leptin, adiponectin, ghrelin) as well as pro-inflammatory cytokines (TNF-α, IL-6 and IL-1), and neuropeptides (α-melanocyte-stimulating hormone and neuropeptide Y) have also been reported as further links between adipose tissue, OS and hypertension [112]. The gene discussed is IL6; the disease is hypertensive disorder.