This raises the possibility that, in some patients, tumour morphology may reflect specific personal features, leading to a form of “individualised tumour morphology.” The significance of the positive cytoplasmic staining obtained with the huntingtin antibody used is not clear, as it is possible that the antibody may react with the normal as well as the abnormal protein which is known to be ubiquitous. This evidence concerns the gene HTT and neoplasm.