A 17-year-old teenager patient, from Los Puertos de Altagracia community (Miranda municipality, Zulia state), who was diagnosed with T1DM on October 2012 after a hyperglycemic crisis complicated with diabetic ketoacidosis, treated only with fast-acting insulin (Crystalline) due to type I hypersensitivity to intermediate-lasting insulin NPH (Neutral Protamine Hagedorn), and long-lasting insulin Glargine (Lantus). The gene discussed is INS; the disease is type 1 diabetes mellitus.