INS and type 1 diabetes mellitus: An association between T1D and vitamin D physiology was suggested by Ponsonby et al. who reported that the pathogenesis of T1D may be dependent on vitamin D receptor variants [10], while studies by Bener et al. [11] and Tunc et al. [12] showed that children with T1D have lower serum 25(OH)D concentration and that these vitamin D-deficient children often require increased amounts of insulin to maintain normal glycemic control [12].