AFP and neoplasm: Table 2 shows that the high PHD2 expression was significantly associated with higher stage (stages III + IV) (OR = 5.576, P < 0.001), bigger tumor size (>5 cm) (OR = 6.176, P < 0.001), poorer differentiation (OR = 1.424, P = 0.003), and higher serum AFP level (OR = 6.861, P < 0.001).