Total KCC2 expression levels at the membrane fraction of the stroke affected side was significantly reduced compared to sham animals and observed to decline to72.5±5.1% in the sham non-affected side at 7 d post-stroke (KCC2: sham non-affected: 100.0±0%, sham-affected: 87.1±4.3%, stroke non-affected: 86.9±5.1%, p<0.05, Fig. 5G). This evidence concerns the gene SLC12A5 and stroke disorder.