DPEP1 and heart failure: (ii) Dipeptidase 1 (DPEP1), a kidney membrane enzyme implicated in renal metabolism and hydrolysation of dipeptides, that showed a distinct membranous expression pattern in exocrine glandular cells, in addition to the brush border of renal tubules (iii) Glycine amidinotransferase (GATM), possibly involved in response to heart failure by elevating local creatine biosynthesis, with a distinct granular expression pattern in exocrine glandular cells, in addition to being highly expressed in kidney and liver.